Jean Smart as Helen Fahey, Mare's mother.Julianne Nicholson as Lori Ross, Mare's closest friend.Kate Winslet as Marianne 'Mare' Sheehan, a detective sergeant in Easttown, Pennsylvania, who is investigating the murder of one young girl and the disappearance of another.
Her personal troubles include a divorce, a son lost to suicide, and a custody battle with her son’s formerly heroin-addicted girlfriend over Mare's grandson. She has also been unable to solve the case of another missing young girl for a year, leading many in the community to doubt her detective skills. Mare is a local hero, having been the star of a high school basketball championship game 25 years earlier. In a suburb of Philadelphia, police detective Marianne 'Mare' Sheehan investigates the recent murder of a teenage mother while trying to keep her own life from falling apart.